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Unlocking the Link Between Alzheimer's Disease, Age-Related Cognitive Decline, and MOLD / Chronic Inflammatory Response Syndrome (CIRS)

The relationship between Alzheimer's Disease, Age-Related Cognitive Decline, and Chronic Inflammatory Response Syndrome (CIRS) is a topic of increasing interest and research. Dr. Dale Bredesen's groundbreaking work has shed light on the multifaceted nature of Alzheimer's Disease, emphasizing the significance of non-genetic factors, including toxins and transcriptomics. It is important for both Alzheimer’s and CIRS patients alike to understand the potential connection between these conditions, and to appreciate the role of CIRS in altering gene expression, revealing a compelling link to cognitive decline.

Alzheimers Disease

Dr. Dale Bredesen's Research: The Six Non-Genetic Causes of Alzheimer's:

Dr. Dale Bredesen, a pioneering neuroscientist, has identified six non-genetic causes of Alzheimer's Disease. These causes challenge the conventional view that Alzheimer's is solely a genetic predisposition.


The six causes are:

1. Inflammation

2. Insulin Resistance

3. Hormone Imbalances and Depleted Nutrients

4. Toxins (including Biotoxins)

5. Vascular Issues

6. Trauma (Impact or Emotional)

Toxins and Transcriptomics:

CIRS as a Toxin-Related Condition: Chronic Inflammatory Response Syndrome (CIRS) is a condition that arises from exposure to biotoxins like mold toxins, Lyme disease, or other environmental contaminants. When the body encounters these toxins, it initiates an immune response, resulting in chronic inflammation throughout the body.

Transcriptomics and Gene Expression: Transcriptomics is the study of how genes are expressed and regulated. In other words, not just what the gene is, but how it is behaving currently. In the context of CIRS, research has shown that exposure to environmental toxins associated with CIRS can significantly impact gene expression.


Here's how:

  • Altered Gene Expression: CIRS-related toxins have been shown to alter gene expression patterns in the body, affecting various cellular processes, including those in the brain.

  • Neuroinflammation: These changes in gene expression can lead to neuroinflammation, a known contributor to cognitive decline.

  • Impact on Brain Function: As gene expression is altered, it can impair essential brain functions, such as memory, learning, and cognitive processing.

The Connection to Cognitive Decline:

The emerging connection between CIRS, toxins, and altered gene expression provides valuable insights into the link between CIRS and cognitive decline:

  • 1. Neuroinflammation: The chronic inflammation triggered by CIRS-related toxins can lead to inflammation in the brain, which is a common feature in Alzheimer's Disease and Age-Related Cognitive Decline.

  • 2. Brain Structure: Altered gene expression may affect the brain's structure and function, potentially contributing to cognitive impairment.

  • 3. Amyloid Accumulation: Some toxins associated with CIRS may interfere with the clearance of amyloid proteins, which are known to accumulate in Alzheimer's Disease.

  • 4. Vascular Dementia: Some transcriptomic changes in CIRS patients suggest an increased risk of vascular dementia due to the changes in gene expression.

How EBHC Treats MOLD/CIRS Patients Who Also Have Alzheimer’s Disease.

EBHC receives patient referrals from qualified physicians who have diagnosed a patient with Alzheimer’s, and the presence of toxins, particularly biotoxins, is a possible contributing factor. In other cases, the families contact EBHC on their own following the diagnosis.

EBHC takes on the role of determining whether the patient meets diagnostic criteria for biotoxin-related illness, and if so, develops a personalized treatment and support plan for the patient and the caregivers, while collaborating with the neurologist or psychiatrist that diagnosed the Alzheimer’s Disease.

The potential connection between Alzheimer's Disease, Age-Related Cognitive Decline, and Chronic Inflammatory Response Syndrome (CIRS) is a subject of ongoing research and discovery. By recognizing the role of toxins and transcriptomics in this complex interplay, we can better understand the link between CIRS and cognitive decline and work toward more effective prevention and intervention strategies. We focus on objective outcomes in CIRS treatment, to ensure that your brain is getting better. In addition, we optimize the other underlying causes of your cognitive decline, alongside CIRS treatment. If you or a loved one is concerned about cognitive health or CIRS, seeking early assessment and embracing a holistic approach may hold the key to preserving mental well-being.

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Other related CIRS symptoms

Fatigue | Weakness | Assimilation of new knowledge | Aching | Headache | Light sensitivity | Memory | Word-finding | Concentration | Joint pain | Morning stiffness | Cramps | Unusual skin sensations | Tingling | Shortness of breath | Sinus congestion | Cough | Excessive thirst | Confusion | Appetite swings | Body temperature regulation | Urinary frequency | Red eye | Blurred vision | Unprovoked sweats | Mood swings | Unusual pains | Abdominal pains | Diarrhea | Numbness | Tearing | Disorientation | Metallic taste | Static shock | Vertigo

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